English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 56859/90577 (63%)
造訪人次 : 12298520      線上人數 : 46
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/98510

    題名: Dynamic Structural Transformation of Resveratrol-Modified Stearate Liposomes Led to a Spontaneous Drug Release System
    作者: Chen, Li-Chou;Lin, Shih-Shan;Li, Cun-Zhao;Hsu, Hsiu-Fu;Weng, Yu-Jong;Cheng, Chien-Chung
    貢獻者: 淡江大學化學學系
    關鍵詞: Liposome;Resveratrol;Stearate;Helical transformation;Drug-release
    日期: 2014-09
    上傳時間: 2014-08-09 16:18:28 (UTC+8)
    出版者: Oxford: Wiley-Blackwell Publishing Ltd.
    摘要: A mono-substituted resveratrol derivative, resveratrol-modified stearate (RMS), was synthesized by selectively coupling of stearic acid to the monohroxyphenyl of resveratrol in order to enhance both the stability and bioavailability of resveratrol. The RMS self-assembles into liposomes and a series of suprastructural transformations into metastable helical ribbon, linear wire-like structures, and inert spherical nanoparticles were detected that may be induced by the hydrogen-bonding interactions. As a model for drug-release investigations, gold nanoparticles (AuNPs) were encapsulated successfully by RMS to generate vesicles and succeed to release AuNPs druing the transformation to a ribbon-like metastable stucture at ambient temperature.
    關聯: Journal of the Chinese Chemical Society 60(9), pp.1099-1102
    DOI: 10.1002/jccs.201300184
    顯示於類別:[化學學系暨研究所] 期刊論文


    檔案 描述 大小格式瀏覽次數



    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回饋