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    Title: Chemoselective Synthesis of β-Amino Ester or β-Lactam via Sonochemical Reformatsky Reaction
    Authors: Lee, Adam Shih-Yuan;Chang, Yu-Ting;Su, Feng-Yi
    Contributors: 淡江大學化學學系
    Keywords: Sonochemical Reformatsky reaction;N-Hydroxy aldimine;β-N-Hydroxyamino ester;β-Lactam
    Date: 2014-02-01
    Issue Date: 2014-03-14 10:14:12 (UTC+8)
    Publisher: Oxford: Wiley-Blackwell Publishing Ltd.
    Abstract: A series of β-amino esters were synthesized by the reaction of N-tosyl aldimine or N-hydroxy aldimine with bromoacetate by sonochemical Reformatsky reaction. The β-N-hydroxyamino ester was obtained and the formed sensitive hydroxylamino functionality was resistant under the reaction condition. The β-lactam also was synthesized by the reaction of N-p-methoxy aldimine as reacting substrate under this sonochemical Reformatsky reaction condition.
    Relation: Journal of the Chinese Chemical Society 61(2), pp.290-294
    DOI: 10.1002/jccs.201300308
    Appears in Collections:[化學學系暨研究所] 期刊論文

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