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    Title: 拉伸應力對紅血球溶血的影響
    Authors: 盧博堅;嚴仁鴻;蔡明勳;邱奕銘;陳曉鐘;陳銘凱
    Contributors: 淡江大學水資源及環境工程學系
    Date: 2013-11-15
    Issue Date: 2014-03-11 15:57:00 (UTC+8)
    Abstract: 本研究以突縮之微細短毛細管做為實驗流場,其在進口端會產生一強烈的拉伸應力場,此流場先經由CFD 的計算,求出其應力值,然後採用豬的新鮮紅血球,進行溶血的測試,以了解拉伸應力對溶血的影響。結果顯示和先前的研究結果是一致的,拉伸應力為紅血球破壞的主要機械力,且其閥值約為1000 Pa。
    In this study, we created a strong extensional stress flow field with the sharp contraction of a short capillary. The flow field generated at the entrance of the capillary was calculated with CFD to determine the stress values, which was followed by hemolysis experiments with porcine red blood cells to determine the effects of extensional stress on hemolysis. Our results were consistent with prior studies in that the extensional stress was the primary mechanical force involved in hemolysis with a threshold value of 1000 Pa.
    Relation: 2013年生物醫學工程科技研討會暨國科會醫學工程學門成果發表會,2頁
    Appears in Collections:[水資源及環境工程學系暨研究所] 會議論文

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