淡江大學機構典藏:Item 987654321/93975
English  |  正體中文  |  简体中文  |  Items with full text/Total items : 62797/95867 (66%)
Visitors : 3735570      Online Users : 640
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/93975


    Title: 銅催化分子內碳-氮鍵偶合反應 : 吲哚酮及菲啶酮的合成
    Other Titles: Copper-catalyzed intramolecular c-n coupling reaction for the synthesis of oxindoles and phenanthridinones
    Authors: 詹于慧;Jhan, Yu-Huei
    Contributors: 淡江大學化學學系碩士班
    謝仁傑;Hsieh, Jen-Chieh
    Keywords: Ullmann反應;串聯反應;螺-吲哚酮;菲啶酮;Ullmann Reaction;Domino Reaction;spiro-oxindoles;phenanthridinones
    Date: 2013
    Issue Date: 2014-01-23 13:45:02 (UTC+8)
    Abstract: 第一部分:
    利用不同方法合成3,3 spiro-oxindole結構的產物並探討反應機構之差異。
    第二部份:
    利用高效率銅催化分子內形成碳-氮鍵,利用起始物鄰溴苯乙醯胺在少量的氧化亞銅和鄰苯二胺空氣中可合成具有高產率的3,3 spiro-oxindole衍生物結構。

    第三部分:
    利用高效率銅催化分子內形成碳-氮鍵,利用起始物2’-bromo-2-cyanodipheny在少量的碘化銅和氫氧化鈉在100℃下可合成具高產率的菲啶酮衍生物結構。
    The 1st Part:
    Variously synthetic methods of 3,3 spiro-oxindole derivatives were carried out and comparison of the mechanisms for different pathway was discussed.
    The 2st Part:
    An efficient copper-catalyzed intramolecular N-arylation was carried out by involving 2,2-substituted 2-(2-bromoaryl)acetamide to afford various substituted oxindoles with a small amount of Cu2O and benzene-1,2-diamine as catalytic system under aerobic conditions, which provided good to excellent yields with tolerance of wide variety of substrates.
    The 3st Part:
    An efficient copper-catalyzed intramolecular N-arylation was carried out by involving 2’-bromo-2-cyanodipheny to afford variously substituted phenanthridinones with a small amount of CuI and Sodium hydroxide at 100 oC, which provided good to excellent yields with tolerance of wide variety of substrates.
    Appears in Collections:[Graduate Institute & Department of Chemistry] Thesis

    Files in This Item:

    File SizeFormat
    index.html0KbHTML226View/Open

    All items in 機構典藏 are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback