Dynamic cell attachment of HepG2 in a microchannel

淡江大學機構典藏 > 工學院 > 機械與機電工程學系暨研究所 > 會議論文 > Item 987654321/93219

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題名:	Dynamic cell attachment of HepG2 in a microchannel
作者:	Yang, Lung-Jieh;Lu, Chieh-Wen;Liang, Jia-Chi;Han, Hsieh-Cheng
貢獻者:	淡江大學機械與機電工程學系
關鍵詞:	microchannel;blood vessels;fractal;PDM
日期:	2013-04
上傳時間:	2013-12-07 10:24:05 (UTC+8)
出版者:	Institute of Electrical and Electronics Engineers ( IEEE )
摘要:	A dynamic filling experiment using PBS with HepG2 tumor cells is performed for observing the attachment behavior in capillaries. A PDMS microchannel mimicking the capillary blood vessel is fabricated by the soft lithography. With treating the PDMS microchannels by different plasmas, the corresponding surface roughness (Ra) data are experimentally measured by AFM. Using these PDMS microchannels well defined by proper Ra values, liquid streams with microbeads and living HepG2 tumor cells are filled in, respectively. The microbead and cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval. Finally, the authors qualitatively discussed the surface roughness effect on the particle or cell attachment in a PDMS microchannel.
關聯:	Proceedings of the 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013), 4p.
顯示於類別:	[機械與機電工程學系暨研究所] 會議論文

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檔案	描述	大小	格式	瀏覽次數
NEMS2013_paper_#108_HepG2.pdf		352Kb	Adobe PDF	473	檢視/開啟

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