淡江大學機構典藏:Item 987654321/93219
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    题名: Dynamic cell attachment of HepG2 in a microchannel
    作者: Yang, Lung-Jieh;Lu, Chieh-Wen;Liang, Jia-Chi;Han, Hsieh-Cheng
    贡献者: 淡江大學機械與機電工程學系
    关键词: microchannel;blood vessels;fractal;PDM
    日期: 2013-04
    上传时间: 2013-12-07 10:24:05 (UTC+8)
    出版者: Institute of Electrical and Electronics Engineers ( IEEE )
    摘要: A dynamic filling experiment using PBS with HepG2 tumor cells is performed for observing the attachment behavior in capillaries. A PDMS microchannel mimicking the capillary blood vessel is fabricated by the soft lithography. With treating the PDMS microchannels by different plasmas, the corresponding surface roughness (Ra) data are experimentally measured by AFM. Using these PDMS microchannels well defined by proper Ra values, liquid streams with microbeads and living HepG2 tumor cells are filled in, respectively. The microbead and cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval. Finally, the authors qualitatively discussed the surface roughness effect on the particle or cell attachment in a PDMS microchannel.
    關聯: Proceedings of the 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013), 4p.
    显示于类别:[機械與機電工程學系暨研究所] 會議論文

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