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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/93219

    Title: Dynamic cell attachment of HepG2 in a microchannel
    Authors: Yang, Lung-Jieh;Lu, Chieh-Wen;Liang, Jia-Chi;Han, Hsieh-Cheng
    Contributors: 淡江大學機械與機電工程學系
    Keywords: microchannel;blood vessels;fractal;PDM
    Date: 2013-04
    Issue Date: 2013-12-07 10:24:05 (UTC+8)
    Publisher: Institute of Electrical and Electronics Engineers ( IEEE )
    Abstract: A dynamic filling experiment using PBS with HepG2 tumor cells is performed for observing the attachment behavior in capillaries. A PDMS microchannel mimicking the capillary blood vessel is fabricated by the soft lithography. With treating the PDMS microchannels by different plasmas, the corresponding surface roughness (Ra) data are experimentally measured by AFM. Using these PDMS microchannels well defined by proper Ra values, liquid streams with microbeads and living HepG2 tumor cells are filled in, respectively. The microbead and cell attachment areas in the PDMS microchannel have been recorded dynamically with 10 min interval. Finally, the authors qualitatively discussed the surface roughness effect on the particle or cell attachment in a PDMS microchannel.
    Relation: Proceedings of the 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (IEEE NEMS 2013), 4p.
    Appears in Collections:[Graduate Institute & Department of Mechanical and Electro-Mechanical Engineering] Proceeding

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