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    Title: Enhancement of prodigiosin production by Serratia marcescens TKU011 and its insecticidal activity relative to food colourants
    Authors: Liang, Tzu-Wen;Chen, Shin-Yi;Chen, Yen-Chern;Chen, Chia-Hung;Yen, Yue-Horng;Wang, San-Lang
    Contributors: 淡江大學生命科學研究所
    Keywords: Allura Red AC;Serratia marcescens;Tartrazine;insecticidal activity;prodigiosin;squid pen
    Date: 2013-11-01
    Issue Date: 2013-10-17 14:39:17 (UTC+8)
    Publisher: Hoboken: Wiley-Blackwell Publishing, Inc.
    Abstract: Prodigiosin (PG) has been reported to have various biological activities. With the aim of increasing Serratia marcescens TKU011 PG production on squid pen powder (SPP)-containing medium, the effects of phosphate and ferrous ion supplementation, autoclave treatment, and aeration were studied. Autoclave treatment showed positive results for PG productivity (2.48 mg/mL), which increased 2.5-fold when the organism was incubated in 50 mL of 40-min autoclaved medium in a baffle-based flask (250 mL) containing 1.5% SPP at 30 °C for 1 day and then at 25 °C for 2 additional days. Furthermore, the use of pigments including PG and the food colorants Allura Red AC (R40) and Tartrazine (Y4) as insecticides was also investigated. The lethal concentrations causing 50% Drosophila larval mortality (LC50) of PG, Y4, and R40 using a 5-d exposure period were 230, 449, and 30000 ppm, respectively. The results indicated that the biopigment PG and the food colorant Y4 were potentially toxic to Drosophila larvae.
    Relation: Journal of food science 78(11), pp.M1743–M1751
    DOI: 10.1111/1750-3841.12272
    Appears in Collections:[化學學系暨研究所] 期刊論文

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