English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 57517/91034 (63%)
造访人次 : 13456848      在线人数 : 322
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻

    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/80049

    题名: Asymmetric composite membranes from chitosan and tricalcium phosphate useful for guided bone regeneration
    作者: Tai, Hung-Yin;Chou, Shiu-Huey;Cheng, Liao-Ping;Hung-Te Yu;Don, Trong-Ming
    贡献者: 淡江大學化學工程與材料工程學系
    2013013113:28 verified by Sujen
    关键词: Chitosan;β-tricalcium phosphate;asymmetric membrane;guided bone regeneration
    日期: 2012-09
    上传时间: 2013-01-17 09:06:18 (UTC+8)
    出版者: Oxfordshire: Taylor & Francis
    摘要: To fulfill the properties of barrier membranes useful for guided bone tissue regeneration in the treatment of periodontitis, in this study a simple process combining lyophilization with preheating treatment to produce asymmetric barrier membranes from biodegradable chitosan (CS) and functional β-tricalcium phosphate (TCP) was proposed. By preheating TCP/CS (3:10, w/w) in an acetic acid solution at 40°C, a skin layer that could greatly increase the mechanical properties of the membrane was formed. The asymmetric membrane with a skin layer had a modulus value almost 4-times that of the symmetric porous membrane produced only by lyophilization. This is beneficial for maintaining a secluded space for the bone regeneration, as well as to prevent the invasion of other tissues. The subsequent lyophilization at -20°C then gave the rest of material an interconnected pore structure with high porosity (83.9-90.6%) and suitable pore size (50-150 μm) which could promote the permeability and adhesiveness to bone cells, as demonstrated by the in vitro cell-culture of hFOB1.19 osteoblasts. Furthermore, the TCP particles added to CS could further increase the rigidity and the cell attachment and proliferation of hFOB1.19. The TCP/CS asymmetric composite membrane thus has the potential to be used as the barrier membrane for guided bone regeneration.
    關聯: Journal of Biomaterials Science: Polymer Edition 23(9), pp.1153-1170
    DOI: 10.1163/092050611X576657
    显示于类别:[化學工程與材料工程學系暨研究所] 期刊論文


    档案 描述 大小格式浏览次数
    Asym CS TCP J Bio mater Sci Polym 2012.pdf1649KbAdobe PDF755检视/开启



    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回馈