L-Proline Catalyzed Condensation Reaction of Aldehyde or Carboxylic Acid with 2-Aminothiophenol under Solvent-Free and Microwave Irradiation

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Title:	L-Proline Catalyzed Condensation Reaction of Aldehyde or Carboxylic Acid with 2-Aminothiophenol under Solvent-Free and Microwave Irradiation
Authors:	Lee, Adam Shih-Yuan;Chung, Ching-Hui;Chang, Yu-Ting;Chen, Pin-Lung
Contributors:	淡江大學化學學系
Keywords:	2-Arylbenzothiazole;2-Aminothiophenol;L-Proline;Microwave Irradiation;Solvent-Free
Date:	2012-11-01
Issue Date:	2013-01-10 13:59:11 (UTC+8)
Publisher:	新北市：淡江大學
Abstract:	A series of 2-arylbenzothiazoles was synthesized from the condensation reaction of aryl aldehyde with 2-aminothiophenol in the presence of L-proline under solvent-free and microwave irradiation conditions. Aromatic acids and aliphatic acids also gave the desired products in good to moderate yields under the reaction conditions. The product yields of using carboxylic acids with 2-aminothiophenol were generally lower than those of using aldehydes. This microwave-assisted L-proline catalyzed reaction provides a green and inexpensive preparation method for synthesis of 2-arylbenzothiazoles.
Relation:	Journal of Applied Science and Engineering 15(3), pp.311-315
DOI:	10.6180/jase.2012.15.3.12
Appears in Collections:	[Graduate Institute & Department of Chemistry] Journal Article

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