English  |  正體中文  |  简体中文  |  Items with full text/Total items : 49287/83828 (59%)
Visitors : 7151162      Online Users : 68
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/76943


    Title: 具共變量誤差之區間設限數據分析
    Other Titles: Analysis of Interval-Censored Data with Mismeasured Covariates
    Authors: 溫啟仲
    Contributors: 淡江大學數學學系
    Keywords: 有效分數;現狀數據;區間設限;測量誤差;Conditional score;current status data;interval censoring;measurement error
    Date: 2011-08
    Issue Date: 2012-05-22 22:16:47 (UTC+8)
    Abstract: 具共變量測量誤差之右設限數資料已被廣泛的研究,但對現狀或區間設限數據卻很 少研究。研究動機的一部分為斑馬魚之基底細胞癌的研究,其中研究者只知道細胞癌的 發生時間在獻祭時間之前或之後,而共變量Sonic hdgehog 基因表現存有量測誤差。因 此,我們對於具共變量測量誤差之(型I 或型k)區間設限資料,在正比例優劣比模型下, 將提出一個「條件分數法」來分析。條件分數法的重要優勢為不需對真實易有誤差卻未 見之共變量作一分佈假設,因此我們所提估計方法將相較其他處理測量誤差方法更具穩 健性。
    Covariate measurement error problems have been extensively studied in the context of right-censored data but less so for current status or interval-censored data. Motivated partly by the zebrafish basal cell carcinoma (BCC) study, where the occurrence time of BCC was only known to lie before or after a sacrifice time and where the covariate (Sonic hedgehog expression) was measured with error, we will propose a conditional score approach to the analysis of (case I / case k) interval-censored data with mismeasured covariates under the proportional odds model. The conditional score approach, originated by Stefanski and Carroll (1987), has the important advantage that it does not need a distributional assumption for unobserved error-prone covariate, rendering the proposed approach more robust and applicable compared to other strategies for handling measurement errors.
    Appears in Collections:[數學學系暨研究所] 研究報告

    Files in This Item:

    There are no files associated with this item.

    All items in 機構典藏 are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback