本研究結果顯示，隅角開放型青光眼在眼內產生的壓力確實存在傳遞的情形並實際影響眼球後方的視神經，導致視神經受到壓迫終究產生視野缺陷。 Primary Open Angle Glaucoma (POAG) is one of the three most common types of glaucoma, and is often associated with family disease history. The major cause for POAG is the adhesion at anterior trabecular meshwork tissue. This makes drainage system fails to function normally in anterior chamber, causes aqueous from anterior chamber hampered, and increased intraocular pressure. Then, Optic nerve is suppressed, optic disc is damaged, and visual field eventually is reduced.
The numerical model constructed in this study is to simulate the mechanism in forming POAG. Aqueous is generated from posterior chamber and flows into anterior chamber. As drainage system hampered, intraocular pressure increases and acts on the lens which creates oppression on vitreous and passes on the impact to optic nerve.
The results show that the pressure in the eyes of primary open angle glaucoma does transmit from lens to vitreous and actually affect the optic nerve on the back of an eye. This leads to optic nerve compression and vision defects.
