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    題名: A Generalized Correlation Coefficient for the General Two-Treatment Crossover Design
    作者: Chen, Vivian Yi-Ju;Chinchilli, Vernon M.
    貢獻者: 淡江大學統計學系
    關鍵詞: Bootstrap;Correlation coefficient;Crossover design;U-Statistics
    日期: 2010
    上傳時間: 2011-10-23 16:23:15 (UTC+8)
    出版者: Philadelphia: Taylor & Francis Inc.
    摘要: This article extends the correlation methodology developed by Chinchilli et al. (2005) for the 2 × 2 crossover design to more complex crossover designs for clinical trials. We describe how the methodology can be adapted to a general type of two-treatment crossover design which includes either at least two sequences or at least two treatment periods or both. We then derive the asymptotic theory for the corresponding correlation statistics, investigate the statistical accuracy of the estimators via bootstrap analyses, and demonstrate their use with two real data examples.
    關聯: Communications in Statistics - Theory and Methods 39(11), pp.2063-2080
    顯示於類別:[統計學系暨研究所] 期刊論文

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