The propagation of sound in long enclosures with branches has been studied theoretically and experimentally, and an efficient combined method is proposed to predict the sound field in long enclosures with branches. Based on the wave-acoustics theory, the theoretical analysis of the sound field of the long enclosures with branches is performed. This paper also investigated the sound field prediction of long enclosures with branches, by using the acoustic modeling program, ODEON. The results obtained by the theoretical analysis and the numerical simulation ODEON are compared with the experimental measurements, and the characteristics of the two methods for predicting the sound field of long enclosures with branches are analyzed. Compared with the experimental results, it is found that: (1) the results predicted by the theoretical analysis fluctuate relatively large with respect to the source–receiver distance, and the sound pressure level (SPL) attenuation obtained is smaller than that measured; and (2) the results predicted by the numerical simulation is smoother, and the calculated SPL attenuation is larger than that measured. To effectively predict the sound field of long enclosures with branches, a combined numerical method is thus proposed. The effectiveness of the proposed combined method is demonstrated by the scale-model experiments.