Novel Fabrication of Full Parylene-Isolated Neuroprobes

機構典藏 > College of Engineering > Graduate Institute & Department of Mechanical and Electro-Mechanical Engineering > Journal Article > Item 987654321/60544

Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/60544

Title:	Novel Fabrication of Full Parylene-Isolated Neuroprobes
Authors:	Lu, Pen-Li;Fan, Chu-Lin;Yang, Lung-Jieh;Lin, Chii-Wann;Jaw, Fu-Shan
Contributors:	淡江大學機械與機電工程學系
Keywords:	Microelectromechanical System (MEMS);Neuroprobe;Parylene;Biocompatible
Date:	2009-06
Issue Date:	2011-10-14 13:41:10 (UTC+8)
Publisher:	Valencia: American Scientific Publishers
Abstract:	A novel 8-channel neuroprobe completely protected by biocompatible parylene C was fabricated in this study. Instead of conventional etching, laser micromachining was utilized to define the sharp tip. Sacrificial aluminum wires were bound on the platinum electrodes, and then the neuroprobes were fully insulated by parylene. Finally the aluminum wires were broken by shear force and etched chemically to expose the electrodes. The shank of the neuroprobe is 7-mm long with a 05×05 mm2 cross-section area. We have used the neuroprobe to record the neuronal responses of rat’s primary somatosensory cortex. Based on the consideration that parylene has good biocompatibility and thus less tissue damage, we believed that this probe could serve the purpose of long-term recording.
Relation:	Journal of Bionanoscience 3(1), pp.58-60
DOI:	10.1166/jbns.2009.1001
Appears in Collections:	[Graduate Institute & Department of Mechanical and Electro-Mechanical Engineering] Journal Article

Files in This Item:

File	Description	Size	Format
32_2009_03Jbns01-1001-07-012.pdf		268Kb	Adobe PDF	4	View/Open
index.html		0Kb	HTML	28	View/Open