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    題名: Membrane fouling mechanism and concentration effect in cross-flow microfiltration of BSA/dextran mixtures
    作者: Hwang, Kuo-Jen;Sz, Pan-Yu
    貢獻者: 淡江大學化學工程與材料工程學系
    關鍵詞: Cross-flow microfiltration;Membrane fouling;Membrane filtration;Bio-separation
    日期: 2011-01
    上傳時間: 2011-10-13 22:34:57 (UTC+8)
    出版者: Amsterdam: Elsevier BV
    摘要: Membrane fouling in BSA/dextran binary suspension cross-flow microfiltration under various operating conditions is studied. The mechanisms for membrane fouling based on the SEM and CSLM observations under various suspension concentrations are proposed. BSA aggregates deposit onto the membrane surface while dextran molecules adsorb into the membrane pores, resulting in filtration resistances. The BSA deposition is mainly determined by the drag forces exerted on BSA aggregates on the membrane surface. Dextran adsorption is affected by the dextran concentration and applied pressure. The concentration effects on the filtration flux and filtration resistance are also discussed. The filtration fluxes for BSA/dextran mixtures are located between those for two pure substances and decrease with the increase in either the BSA or dextran concentration. However, the dextran concentration impact is more significant because the filtration resistance caused by membrane blocking is much higher than that caused by cake formation in most conditions. The filtration resistances due to concentration polarization, cake formation and membrane internal fouling can be estimated directly from the operating conditions using the semi-theoretical methods proposed in this study.
    關聯: Chemical Engineering Journal 166(2), pp.669–677
    DOI: 10.1016/j.cej.2010.11.044
    顯示於類別:[化學工程與材料工程學系暨研究所] 期刊論文

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