English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 57978/91504 (63%)
造访人次 : 13695274      在线人数 : 59
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/53089


    题名: The effect of ultra-nanocrystalline diamond films on the proliferation and differentiation of neural stem cells
    作者: Chen, Ying-Chieh;Lee, Don-Ching;Hsiao, Chao-Yang;Chung, Yu-Fen;Chen, Huang-Chin;Joseph P. Thomas;Pong, Way-Faung;Tai, Nyan-Hwa;Lin, I-Nan;Chiu, Ing-Ming
    贡献者: 淡江大學物理學系
    关键词: Neural stem cells;Neural differentiation;Ultra-nanocrystalline diamond;ECM
    日期: 2009-07
    上传时间: 2010-12-23 13:55:46 (UTC+8)
    出版者: Amsterdam: Elsevier BV
    摘要: The interaction of ultra-nanocrystalline diamond (UNCD) with neural stem cells (NSCs) has been studied along with its surface modification in order to improve its function as a biomaterial. Hydrogen- and oxygen-terminated UNCD films were compared with standard grade polystyrene in terms of their impact on the growth, expansion and differentiation of NSCs. When NSCs were cultured on these substrates in low serum and without any differentiating factors, hydrogen-terminated UNCD films spontaneously induced cell proliferation and neuronal differentiation. Oxygen-terminated UNCD films were also shown to further improve neural differentiation, with a preference to differentiate into oligodendrocytes. Hence, controlling the surface properties of UNCD could manipulate the differentiation of NSCs for different biomedical applications. These observations raise the potential for the use of UNCD as a biomaterial for central nervous system transplantation and tissue engineering.
    關聯: Biomaterials 30(20), pp.3428-3435
    DOI: 10.1016/j.biomaterials.2009.03.058
    显示于类别:[物理學系暨研究所] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    0142-9612_30(20)p3428-3435.pdf967KbAdobe PDF1检视/开启
    index.html0KbHTML361检视/开启

    在機構典藏中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回馈