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    题名: Attachment of tumor cells to the micropatterns of glutaraldehyde (GA)-crosslinked gelatin
    作者: Ou, Yu-cheng;Hsu, Chih-wen;楊龍杰;Yang, Lung-jieh;Han, Hsieh-cheng;Liu, Yi-wen;Chen, Chien-yuan
    贡献者: 淡江大學機械與機電工程學系
    关键词: gelatin;glutaraldehyde;tumor cells;attachment
    日期: 2008
    上传时间: 2010-08-10 15:25:24 (UTC+8)
    出版者: Scientific Publishing Division Myu
    摘要: In this work, we propose a novel technique for inducing the attachment of tumor cells to the micropatterns of glutaraldehyde (GA)-crosslinked gelatin. It provides another method to crosslink gelatin other than using photosensitizing agents or selective GA crosslink techniques. This novel technique can ensure the degree of crosslink, prevent an over-crosslink from pattern deformation and enhance the adhesion between gelatin and a glass slide. The best spatial resolution of micro-gelatin bases can be 2 μm. The micropatterns of GA-crosslinked gelatin can still be formed successfully by conventional photolithography. The much less toxic and more biocompatible approaches of strengthening gelatin microstructures can be developed according to the idea herein.
    關聯: Sensors and Materials 20(8), pp.435-446
    显示于类别:[機械與機電工程學系暨研究所] 期刊論文


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