淡江大學機構典藏:Item 987654321/44670
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    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/44670


    Title: Turbulence Characteristics Downstream of Bileaflet Aortic Valve Prostheses
    Authors: 劉佳興;Liu, Jia-Shing;盧博堅;Lu, Po-chien;Chu, Shu-hsun
    Contributors: 淡江大學水資源及環境工程學系
    Date: 1999-08-22
    Issue Date: 2010-03-26 16:39:05 (UTC+8)
    Publisher: American Society of Mechanical Engineers (ASME)
    Abstract: This study was focused on a series of in vitro tests on the turbulent flow characteristics of three bileaflet aortic valves: St. Jude Medical (SJM), CarboMedics (CM), and Edwards Tekna (modified Duromedics, DM). The flow fields of the valves were measured in a pulsatile flow model with a laser-Doppler anemometer (LDA) at the aortic sinus area downstream of the valves. The heart rate was set at 70 beats per minute, the cardiac output was maintained at 5 liters per minute, and the aortic pressure wave forms were kept within the physiological range. Cycle-resolved analysis was applied to obtain turbulence data, including mean velocity, Reynolds stresses, autocorrelation coefficients, energy spectral density functions, and turbulence scales. The Reynolds shear stresses of all three valves induced only minor damage to red blood cells, but directly damaged the platelets, increasing the possibility of thrombosis. The smallest turbulence length scale, which offers a more reliable estimate of the effects of turbulence on blood cell damage, was three times the size of red blood cells and five times the size of platelets. This suggests that there is more direct interaction with the blood cells, thus causing more damage.
    Relation: Journal of biomechanical engineering 122(2), p.118-124
    DOI: 10.1115/1.429643
    Appears in Collections:[Graduate Institute & Department of Water Resources and Environmental Engineering] Journal Article

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