Electrophoresis of biological cells:charge-regulation and multivalent counterions association model

doi:10.1002/elps.200390172

淡江大學機構典藏 > 理學院 > 數學學系暨研究所 > 期刊論文 > Item 987654321/41230

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題名:	Electrophoresis of biological cells:charge-regulation and multivalent counterions association model
作者:	Hsu, Jyh-ping;Hseih, Tien-Shiang;Young, Tai-Horng;曾琇瑱;Tseng, Shio-jenn
貢獻者:	淡江大學數學學系
日期:	2003-04-01
上傳時間:	2010-01-28 07:01:20 (UTC+8)
出版者:	Wiley-Blackwell
摘要:	The electrophoresis of a biological cell is analyzed theoretically. An entity, which is of amphoteric nature, is used to simulate its electrophoretic behavior. To reflect conditions of practical interest, we assume that the liquid phase contains mixed (a:b)+(c:b) electrolytes, where a and c are the valences of cations, and b is the valence of anions. We consider the case where the surface of a cell contains both bivalent acidic and monovalent basic functional groups, the dissociation/association of them yields fixed surface charge, and the multivalent cations in the liquid phase are allowed to combine with dissociated acidic functional groups, which has the effect of lowering the charge density on cell surface. The electrophoretic behaviors of a cell under various conditions are illustrated. The results obtained can be used to identify the types of functional groups that may be present on cell surface. On the other hand, if the surface functional groups involved in cell electrophoresis are known, then their density and the associated dissociation/association constants can be estimated from experimental data.
關聯:	Electrophoresis 24(9), pp.1338-1346
DOI:	10.1002/elps.200390172
顯示於類別:	[數學學系暨研究所] 期刊論文

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