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    題名: 幾丁聚醣複合薄膜的製備與抗菌測試
    其他題名: Preparation and Antibacterial Test of Chitosan/PEGDA/PAA Composite Membrane
    作者: 董崇民;Don, Trong-ming;李志剛;鄭廖平;陳慶鐘;Chen, Ching-chung
    關鍵詞: 幾丁聚醣;複合膜;抗菌活性測試;聚乙二醇二丙烯酸酯;聚丙烯酸;Chitosan;Composite Membrane;Antibacterial Activity Test;Polyethylene Glycol Diacrylate;Polyacrylic Acid
    日期: 2003-09-26
    上傳時間: 2010-01-11 11:53:18 (UTC+8)
    摘要: 本研究係利用含有二感光性官能基之寡聚物PEGDA、丙烯酸(Acrylic acid)單體及光起始劑之感光組成物塗佈於不同基材後,加以紫外光硬化處理形成薄膜。進一步,將幾丁聚醣溶於丙烯酸水溶液中並均勻塗佈於薄膜上,其中丙烯酸能發揮偶合劑之效用,擴散至薄膜中使幾丁聚醣植於薄膜表面。藉由控制幾丁聚醣之濃度使表層幾丁聚醣厚度達到奈米層級,因幾丁聚醣具有抗菌效果,故可製備出奈米級之抗菌複合薄膜。利用電子顯微鏡(FESEM)、接觸角(Contact angle)測試及 X射線光電子分析儀(ESCA)來作表面分析,並使用大腸桿菌Escherichia coli.及金黃色葡萄球菌Staphylococcus aureus來作抗菌測試。
    Dopes prepared by blending of polyethylene glycol diacrylate (PEGDA), acrylic acid and a photoinitiator were cast and then UV cured on various substrates to form dense membranes. Subsequently, the later was coated with a layer of solution composed of chitosan, acrylic acid and water. As the acrylic acid diffused into the underneath membrane, chitosan coagulated into a nano-layer on the top. The morphology of the formed composite membrane was observed by low voltage FESEM. The contact angle measurement indicates a top surface consisted of high proportion of chitosan. The antibacterial activities of the membranes were examined with respect to a gram-negative (Escherichia coli) and a gram-positive bacteria (Staphylococcus aureus).
    關聯: 2003幾丁質幾丁聚醣研討會與年會大會手冊論文集=Proceedings of 2003 Taiwan Chitin Chitosan Symposium & Agenda of Society Annual Meeting,頁172-175
    顯示於類別:[化學工程與材料工程學系暨研究所] 會議論文

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