English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 56431/90260 (63%)
造訪人次 : 11699020      線上人數 : 23
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/34791


    題名: 環氧基化合物修飾幾丁聚醣的合成與性質
    其他題名: Synthesis and properties of epoxide-modified chitosan
    作者: 方裕榮;Fang, Yu-jung
    貢獻者: 淡江大學化學工程與材料工程學系碩士班
    董崇民;Don, Trong-ming
    關鍵詞: 幾丁聚醣;鄰苯二甲酸酐;二環氧基醚聚;乙二醇;Chitosan;Phthalic anhydride;Poly(ethylene glycol) diglycidyl ether
    日期: 2005
    上傳時間: 2010-01-11 05:36:53 (UTC+8)
    摘要: 本研究是將幾丁聚醣溶於甲酸溶劑中,再加到N,N-二甲基甲醯胺與鄰苯二甲酸酐的溶液系統中,進行均相的化學反應修飾,利用鄰苯二甲酸酐與幾丁聚醣的胺基反應,藉此保護胺基及改善其有機溶劑溶解性。分別利用元素分析與紫外線可見光光譜分析求出鄰苯二甲酸酐之取代度,在相同反應的條件下,兩種不同方法求出來的結果彼此吻合。利用紅外線光譜及固態核磁共振光譜針對產物作結構分析,結果顯示在高溫反應下,幾丁聚醣確實與鄰苯二甲酸酐有化學反應,且隨著反應時間的增加而有取代度增加的趨勢。反應後之產物可溶於如N,N-二甲基甲醯胺、N,N-二甲基乙醯胺和二甲亞碸有機溶劑。再利用幾丁聚醣上的氫氧基與二環氧基醚聚乙二醇進行接枝反應,並加入陽離子型光起始劑,以UV光交聯得到幾丁聚醣二環氧基醚聚乙二醇接枝的產物,利用元素分析求出取代度。之後再利用聯胺去保護還原幾丁聚醣的胺基,並針對產物作結構分析、熱分析以及澎潤比等測試,藉以評估聚乙二醇接枝幾丁聚醣材料的性質和其它方面的應用性。
    In this study, chitosan was dissolved in formic acid and modified with phthalic anhydride in N,N-dimethylformamide (DMF), through the reaction of amino group with anhydride group. In this way, chitosan can be dissolved in organic solvent. The results show that the degree of substitution increased with reaction time. In addition, the modified chitosan could be dissolved in several organic solvents, such as DMF、DMAc and DMSO. After reaction, the available hydroxyl group in the chitosan was used to graft synthetic polymers onto chitosan chains with poly(ethylene glycol) diglycidyl ether. Photoinitiator (UVI-6992) was added to prepare PEG-graft-PACS copolymers by UV radiation. Then hydrazine monohydrate was employed to deprotect the phthaloyl group. FTIR and NMR were used to analyze the chemical structures of copolymers. DSC and TGA were employed to measure the thermal properties of the prepared copolymers. Swelling ratio was measured to understand the swelling behaviors at different pH values in order to evaluate potential applications of PEG-graft-CS copolymers .
    顯示於類別:[化學工程與材料工程學系暨研究所] 學位論文

    文件中的檔案:

    檔案 大小格式瀏覽次數
    0KbUnknown324檢視/開啟

    在機構典藏中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回饋