Abstract: | 本論文合成具兒茶酚及半醌配位基的鐵(Ⅲ)錯合物(1)~(4),性質及其物性由X-ray單晶繞射儀、UV-Vis光譜、元素分析儀、電化學、電子順磁共振光譜及紅外線光譜方法來分析。 具半醌及兒茶酚配位基錯合物: (1) [Fe(L1)(C6Cl4O2)]2‧OCH3 (2) [Fe(L2)(C6Cl4O2)Cl2] (3) [Fe(L2)(C6Cl4O2)2] (4) [Fe(L3)(C6Cl4O2)2]CH3CN‧CH3OH L1: 2-((E)-(2-(2-aminoethylamino)ethylimino)methyl)phenol L2:(E)-N1-(2-(dimethylamino)ethyl)-N2-((5-methyl-1H-imidazol-4-yl)methylene) ethane-1,2-diamine L3: N,N-diethyl-2-(2-(pyridin-2-yl)imidazolidin-1-yl)ethanamine
錯合物(1)~(4)對1,2雙加氧酶在甲醇溶液中的反應活性,由添加入四種不同的兒茶酚陰離子tetrabromocatechol(TBC), tetrachlorocatechol(TCC), catechol(HC),和3,5-di-tert-butylcatechol(3,5-DTBC)與[Fe(L1)Cl2]、[Fe(L2-3)Cl3]反應,根據吸收位置與路易士酸性的關係可發現,路易士酸性越強的錯合物[Fe(L2) 3,5-DTBC]有較佳加氧酶的催化反應性。 The following complexes(1)~(4) with catecholate and semiquinone ligands were synthesized and physical properties of complexes(1)~(4) were measured by X-ray Single diffraction, UV-Vis spectroscopy, infrared spectra, element analyzer, and Electronchemical analysises. Iron(Ⅲ) complexes with catecholate and semiquinone ligands were prepared: (1) [Fe(L1)(C6Cl4O2)]2‧OCH3 (2) [Fe(L2)(C6Cl4O2)Cl2] (3) [Fe(L2)(C6Cl4O2)2] (4) [Fe(L3)(C6Cl4O2)2]CH3CN‧CH3OH L1: 2-((E)-(2-(2-aminoethylamino)ethylimino)methyl)phenol L2:(E)-N1-(2-(dimethylamino)ethyl)-N2-((5-methyl-1H-imidazol-4-yl)methylene) ethane-1,2-diamine L3: N,N-diethyl-2-(2-(pyridin-2-yl)imidazolidin-1-yl)ethanamine
The methanol solutions of complexes(1)~(4) were titrated with catecholate anions of tetrabromocatechol(TBC), tetrachlorocatechol(TCC), catechol(HC), and 3,5-di-tert-butylcatechol(3,5-DTBC). The results show that the high lewis acidity iron(III) complexes [Fe(L2) 3,5-DTBC] exhibits the higher catechol 1,2-dioxygenase reactivity. |