English  |  正體中文  |  简体中文  |  Items with full text/Total items : 51771/86989 (60%)
Visitors : 8366330      Online Users : 121
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/25213

    Title: Site-Selective DNA Photocleavage Involving Unusual Photoinitiated Tautomerization of Chiral Tridentate Vanadyl(V) Complexes Derived from N-Salicylidene α-Amino Acids
    Authors: Chen, Chien-tien;Lin, Jin-sheng;Kuo, Jen-huang;Weng, Shiue-shien;Cuo, Ting-shen;Lin, Yi-wen;鄭建中;Cheng, Chien-chung;Huang, Yan-chen;Yu, Jen-kan;Chou, Pi-tai
    Contributors: 淡江大學化學學系
    Date: 2004-11-25
    Issue Date: 2009-12-01
    Publisher: American Chemical Society (ACS)
    Abstract: The titled vanadyl(V) complexes serve as efficient reagents for cleaving supercoiled plasmid DNA by photoinitiation. Complex 3d, derived from 2-hydroxy-1-naphthaldehyde and l-phenylalanine, exhibits a unique wedge feature, inducing a site-selective photocleavage at the C22-T23 of the bulge backbone for a HIV-27 DNA system at 0.1−5 μM. Transient absorption experiments for 3d indicate the involvement of LMCT with concomitant tautomerization, leading to an o-quinone-methide V-bound hydroxyl species responsible for the cleavage profiles.
    Relation: Organic letters 6(24), pp.4471-4474
    DOI: 10.1021/ol048156h
    Appears in Collections:[化學學系暨研究所] 期刊論文

    Files in This Item:

    File SizeFormat

    All items in 機構典藏 are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback