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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/25126

    Title: pH Dependent Thermal Stabilization of DNA by Glcβ(1→3)GlcNAcβ1→Stol
    Authors: Lin, Chun-cheng;Hung, Sue-mei;Lee, Kuo-cheng;鄭建中;Cheng, Chien-chung
    Contributors: 淡江大學化學學系
    Keywords: DNA-carbohydrate interaction;Hydrogen-bond;pH dependent;Thermal stabilization.
    Date: 2004-06-01
    Issue Date: 2013-07-29 13:41:14 (UTC+8)
    Publisher: 臺北市:中國化學學會
    Abstract: A disaccharide, Glcβ(1→3)GlcNAcβ1→Stol (GGS, 1), was synthesized and demonstrated to stabilize ct-DNA during the denaturing process. GGS at 50 μM shifted Tm of ct-DNA by 23 °C and the behavior was pH dependent. Poly(dA-dT)2 was found to be the preferable type of DNA for GGS stabilization by circular dichroism spectroscopy study.
    Relation: Journal of the Chinese Chemical Society=中國化學會會誌 51(3), pp.655-658
    DOI: 10.1002/jccs.200400098
    Appears in Collections:[化學學系暨研究所] 期刊論文

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