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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/24911


    Title: Cytotoxic Prenylflavanones from Taiwanese Propolis
    Authors: Chen, Chia-nan;吳嘉麗;Wu, Chia-li;Shy, Horng-shing;Lin, Jen-kun
    Contributors: 淡江大學化學學系
    Date: 2003-04-01
    Issue Date: 2009-12-01
    Publisher: American Chemical Society (ACS)
    Abstract: Two new prenylflavanones, propolin A (2) and propolin B (3), were isolated and characterized from Taiwanese propolis. Both compounds were found to have cytotoxic properties against three cancer cell lines. DNA content analyses and DNA fragmentation indicated that propolin A (2) efficiently induced apoptosis in cancer cell lines, but had no effect on the cell cycle program. Furthermore, both propolin A (2) and B (3) are potential antioxidant agents and show strong scavenging effects against most types of free radicals.
    Relation: Journal of natural products 66(4), pp.503-506
    DOI: 10.1021/np0203180
    Appears in Collections:[化學學系暨研究所] 期刊論文

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