This paper studies the relationship between career orientation and performance of R&D professionals in Taiwanese high-tech firms. 385 R&D professionals of electronics and information/communication industry in Taiwan are selected, and 223 returned questionnaires were studied. The relationship is found between the organizational characteristics and career orientation of R&D professionals in the high-tech firms. In addition, the performance of samples th4t career orientation corresponds to the current position is higher than the others. Discussion and the implication for the career Orientation of R&D professionals in Taiwanese high-tech firms are provided.