淡江大學機構典藏:Item 987654321/129369
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    題名: Scandium-Catalyzed Fischer Indole Synthesis: A Highly Efficient Construction of Complicated Indoles
    作者: Thorat, Vijaykumar H.;Chao, Hao-Yu;Yang, Po-Han;Hsieh, Jen-Chieh
    關鍵詞: Fischer indole synthesis;Scandium;Catalysis;Cyclization;Heterocycle
    日期: 2025-02-03
    上傳時間: 2026-07-03 12:05:34 (UTC+8)
    出版者: Wiley-VCH
    摘要: Herein, we report an efficient scandium-catalytic reaction protocol for the classical Fischer indole synthesis, which can tolerate a wide variety of polycyclic substrates and allow us to easily construct complex indole structures in high yields for most cases. Moreover, in order to demonstrate the reaction efficacy, we also synthesized two quinazolinone-containing natural alkaloids, their analog, as well as an anticancer indenoindolone compound.
    關聯: European Journal of Organic Chemistry 28(5), e202401194
    DOI: 10.1002/ejoc.202401194
    顯示於類別:[化學學系暨研究所] 期刊論文

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