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https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/129193
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| Title: | Advances in liquid crystal-based sensors driven by nanotechnology: Mechanisms, materials, and emerging trends |
| Authors: | Nandi, Rajib;Saeed, Muhammad Umer;Chen, Chih-Hsin |
| Keywords: | Liquid crystal-based sensors;Nanomaterials;Nanostructured surfaces;Nanoparticle-enhanced sensing;Gas detection;Environmental monitoring |
| Date: | 2025-09-03 |
| Issue Date: | 2026-04-16 12:05:25 (UTC+8) |
| Abstract: | Liquid crystals (LCs) are unique chemo-responsive materials whose orientational order responds to chemical or physical stimuli at interfaces, producing optical changes observable to the naked eye or measurable via simple optical methods. This property enables LC-based sensors to offer label-free, real-time, and sensitive detection. The incorporation of nanostructured materials introduces new sensing mechanisms and enhances signal outputs through increased surface interactions, localized plasmonic effects, and specific molecular interactions with LC molecules. Unlike other nano-enhanced platforms, LC-based sensors uniquely utilize the collective reorientation of LC molecules to generate macroscopically visible optical signals without the need for sophisticated instrumentation. When combined with the tunable properties of nanomaterials, these systems offer high sensitivity, specificity, and real-time visualization capabilities. This review categorizes nanomaterial integration strategies in LC-based sensors into six key approaches: (1) signal enhancement in LC-based immunosensors, (2) signal enhancement in LC based-DNA/aptamer sensors, (3) dual-signal generation through electro-optic properties, (4) signal amplification at aqueous interfaces, (5) in-situ nanoparticle formation within LC systems, and (6) modulation of LC ordering using nanostructured surfaces. We also discuss current challenges and future opportunities, including scalable fabrication, AI-assisted image analysis, and wearable commercial sensing devices. This review provides a comprehensive perspective on nanomaterial-enhanced LC sensors and offers insights into the design of next-generation chemical and biosensing platforms. |
| Relation: | Sensors and Actuators B: Chemical 446 ,p. 138684 |
| DOI: | 10.1016/j.snb.2025.138684 |
| Appears in Collections: | [Graduate Institute & Department of Chemistry] Journal Article
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