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    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/128151


    Title: Effects of Participation in Volunteer Activities on CD34+ Hematopoietic Stem Cells
    Authors: Chang, Chuan-Hsin;Chen, Chia-Chi;Chang, Yue-Cune;Hsieh, Cho Chen;Lin, Chai Ching;Lee, Jia-Fu
    Keywords: effects;volunteer activities;CD34+;hematopoietic stem cells
    Date: 2025/09/20
    Issue Date: 2025-10-23 12:06:01 (UTC+8)
    Publisher: Sage
    Abstract: Aging populations face health challenges, and volunteering may improve health outcomes. This study investigated
    the relationship between volunteering, CD34+ hematopoietic stem cells, and health indicators in older adults.
    The sample included 91 participants aged 65 to 75, with 52 reporting prior volunteering involvement. Evaluations
    comprised the Geriatric Depression Scale (GDS), Mini-Mental State Examination, Clinical Dementia Rating scale, and
    Neuropsychiatric Inventory. Blood analyses measured CD34+ hematopoietic stem cells and CD34+ lymphocytes.
    Multiple linear regression assessed variations in CD34+ counts and related metrics among groups, adjusting for
    confounding factors. Volunteers exhibited enhanced cognitive functioning and lower depression levels compared to
    non-volunteers, as reflected in GDS scores of 4.29 ± 4.18 versus 8.26 ± 5.09 (p < .001). Furthermore, volunteers
    had notably elevated CD34+ stem cell and lymphocyte counts, suggesting volunteering positively influences this
    health marker. Participation in volunteer activities is linked to improved cognitive abilities, reduced depressive
    symptoms, and heightened CD34+ hematopoietic stem cell levels. Findings underscore the potential health benefits
    of volunteering for older adults, necessitating further investigation into the mechanisms and enduring effects of
    volunteerism on health, with CD34+ cell counts identified as a significant biomarker for cognitive and emotional
    health enhancements in this population
    Relation: Sage Open Aging 11, p.1-8
    DOI: 10.1177/30495334251385836
    Appears in Collections:[應用數學與數據科學學系] 期刊論文

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