A simulation study on adaptive assignment versus randomizations in clinical trials

淡江大學機構典藏 > 商管學院 > 財務金融學系暨研究所 > 期刊論文 > Item 987654321/126618

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题名:	A simulation study on adaptive assignment versus randomizations in clinical trials
作者:	Chien-Tai, Lin 1;Yun-Wei, Li 2;Hong, Yi-Jun
关键词:	adaptive procedures;conditional probability lost;play-the-winner/switch-from-a-loser;randomization methods;robust Bayes
日期:	2024-12-26
上传时间:	2024-12-27 12:05:30 (UTC+8)
摘要:	This study investigates a sequential clinical trial comparing two treatments with dichotomous outcomes. We evaluate the effectiveness of five adaptive procedures and three randomization methods for assigning patients to different therapies. The primary objective is to identify an optimal treatment allocation policy that maximizes the proportion of successful outcomes in a trial. By comparing the performance of adaptive and randomized procedures, this research provides valuable insights for enhancing treatment allocation strategies in clinical trials, ultimately aiming to improve the overall success rates of therapeutic interventions.
關聯:	Mathematics, 13, 44.
DOI:	10.3390/math13010044
显示于类别:	[財務金融學系暨研究所] 期刊論文

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