Prognostic Factors of Cirrhotic Patients with Invasive Fungal Infections

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題名:	Prognostic Factors of Cirrhotic Patients with Invasive Fungal Infections
作者:	Hung, Tsung-Hsing;Ko, Ping-Hung;Tsai, Chih-Chun;Wang, Chih-Ying;Lee, Hsing-Feng
關鍵詞:	cirrhosis;invasive fungal infections;prognosis
日期:	2023-10-27
上傳時間:	2024-03-11 12:05:21 (UTC+8)
摘要:	Fungal infection (FI) is a life-threatening condition in cirrhotic patients. However, a population-based study is required to determine the short-term mortality of these patients. The Taiwan National Health Insurance Database was used to enroll 1214 cirrhotic patients with FIs who were hospitalized between January 1, 2010 and December 31, 2013. Among them, 165 were diagnosed with invasive FIs. The overall 30-day and 90-day mortality rates for patients with invasive FIs were 25.7% and 49.9%, respectively (P < .001). After adjusting for sex, age, and other comorbidities, the following 90-day mortality prognostic factors were statistically different: renal function impairment (hazard ratio = 1.98, 95% confidence interval = 1.05-3.70, P = .034), concurrent with bacterial infections (hazard ratio = 1.75, 95% CI = 1.07-2.88, P = .027). Half of the cirrhotic patients died within 90-daysdue to invasive FIs, highlighting the importance of renal function impairment and concurrent with bacterial infections as an important prognostic factor.
關聯:	Medicine 102(43), e35737
DOI:	10.1097/md.0000000000035737
顯示於類別:	[資訊工程學系暨研究所] 期刊論文

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