Prognostic Factors of Cirrhotic Patients with Invasive Fungal Infections

淡江大學機構典藏 > 工學院 > 資訊工程學系暨研究所 > 期刊論文 > Item 987654321/125247

Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/125247

Title:	Prognostic Factors of Cirrhotic Patients with Invasive Fungal Infections
Authors:	Hung, Tsung-Hsing;Ko, Ping-Hung;Tsai, Chih-Chun;Wang, Chih-Ying;Lee, Hsing-Feng
Keywords:	cirrhosis;invasive fungal infections;prognosis
Date:	2023-10-27
Issue Date:	2024-03-11 12:05:21 (UTC+8)
Abstract:	Fungal infection (FI) is a life-threatening condition in cirrhotic patients. However, a population-based study is required to determine the short-term mortality of these patients. The Taiwan National Health Insurance Database was used to enroll 1214 cirrhotic patients with FIs who were hospitalized between January 1, 2010 and December 31, 2013. Among them, 165 were diagnosed with invasive FIs. The overall 30-day and 90-day mortality rates for patients with invasive FIs were 25.7% and 49.9%, respectively (P < .001). After adjusting for sex, age, and other comorbidities, the following 90-day mortality prognostic factors were statistically different: renal function impairment (hazard ratio = 1.98, 95% confidence interval = 1.05-3.70, P = .034), concurrent with bacterial infections (hazard ratio = 1.75, 95% CI = 1.07-2.88, P = .027). Half of the cirrhotic patients died within 90-daysdue to invasive FIs, highlighting the importance of renal function impairment and concurrent with bacterial infections as an important prognostic factor.
Relation:	Medicine 102(43), e35737
DOI:	10.1097/md.0000000000035737
Appears in Collections:	[資訊工程學系暨研究所] 期刊論文

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