淡江大學機構典藏:Item 987654321/123182
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 64185/96959 (66%)
造访人次 : 11340717      在线人数 : 156
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    淡江大學機構典藏 > 體育事務處 > 期刊論文 >  Item 987654321/123182


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/123182


    题名: Effects of swimming training on myocardial protection in rats
    作者: Chang-Chi Lai, Chia-Yu Tang, Szu-Kai Fu, Wei-Chin Tseng, Kuo-Wei Tseng
    关键词: swimming training;myocardial ischemia-reperfusion;ischemic precondition;coronary artery occlusion;apoptosis
    日期: 2022-01-31
    上传时间: 2023-04-28 17:12:02 (UTC+8)
    出版者: Spandidos Publications
    摘要: Swimming is important for promoting and maintaining health, as it can increase the efficiency of the cardiovascular system and decrease the occurrence of cardiovascular diseases. The objective of the present study was to examine whether swimming training could decrease myocardial injury in rats caused by myocardial ischemia/reperfusion (I/R). Sprague-Dawley rats were randomized into four groups, namely the Sham, coronary artery occlusion, swimming training and ischemic preconditioning (IPC) groups. Myocardial I/R was induced in anesthetized male Sprague-Dawley rats by a 40-min occlusion followed by a 3-h reperfusion of the left anterior descending coronary artery. The rats were sacrificed after surgery and their hearts were examined. The results demonstrated that the number of TUNEL-positive nuclei and degree of caspase-3 activation were both significantly increased in the myocardium following myocardial I/R in rats, indicating increased cardiomyocyte apoptosis. On the other hand, swimming training decreased the serum levels of creatine phosphokinase, lactate dehydrogenase and cardiac troponin I, and was associated with reduced histological damage and myocardial infarct size. Furthermore, swimming training also reduced TNF-α levels, caspase-3 activation and enhanced Bcl-2 activation, which decreased the number of apoptotic cells in the myocardium. The findings of the present study showed that swimming training and IPC could similarly decrease myocardial injury following myocardial I/R, and may therefore be used as exercise training to effectively prevent myocardial injury.
    關聯: Biomedical Reports, 16(19)
    DOI: 10.3892/br.2022.1502
    显示于类别:[體育事務處] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML177检视/开启

    在機構典藏中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回馈