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    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/121848

    Title: Rapid Detection of Glucose on Nanostructured Gold Film Biosensor by Surface-Enhanced Raman Spectroscopy
    Authors: Chao, Szu-Han;Hsu, Shih-Chieh
    Date: 2022-01-07
    Issue Date: 2022-01-04 12:13:30 (UTC+8)
    Abstract: In this report, we summarized our development of biosensors for Rhodamine 6G and in
    vitro glucose detection based on surface-enhanced Raman scattering technology. For the
    detection of both Rhodamine 6G and in vitro glucose, a nature-patterned substrate with gold
    films over nanostructures (NPS-AuFON) was used as the surface-enhanced Raman scattering
    sensor platform. The enhancement factor was calculated at 9 × 107

    . In the processing of the
    substrate, cyclic voltammetry was used to form nano-gold particles under different conditions.
    The Rhodamine 6G and glucose detection were then achieved on this substrate. Furthermore,
    we combined the potentiostatic technique and electrochemical adsorption to best detect glucose
    in low concentrations. The glucose oxidation potential (100 mV) was used to capture glucose
    close to the surface of the NPS-AuFON. The quantitative detection of glucose in solution and
    in situ inspection were confirmed. Further, we determined that this surface modification
    technology can reach the goal of experiments set by the World Health Organization to judge
    whether or not a patient is a diabetic by detecting a glucose concentration of 11.1 mmol/L
    (mg/dL) at a minimum.
    Relation: 68rd TwICHE Annual Conference
    Appears in Collections:[Graduate Institute & Department of Chemical and Materials Engineering] Proceeding

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