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    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/120994


    Title: Associations Between Lifestyle Factors and Reduced Kidney Function in US Older Adults: NHANES 1999–2016
    Authors: Chang, Horng-Jinh;Lin, Kuan-Reng;Lin, Meng-Te;Chang, Junn-Liang
    Keywords: chronic kidney disease;estimated glomerular filtration rate;exercise;kidney function;risk factors
    Date: 2021-07-15
    Issue Date: 2021-08-23 12:14:01 (UTC+8)
    Publisher: Swiss School of Public Health
    Abstract: Objective: This study aimed to evaluate the associations between lifestyle factors and the
    estimated glomerular filtration rate (eGFR) levels in older adults by analyzing the
    United States National Health and Nutrition Examination Survey data (1999–2016).
    Methods: A total of 10,052 eligible participants were divided into two groups: reduced
    eGFR group (eGFR < 60 ml/min/1.73 m2
    ) and normal group (eGFR ≥ 60 ml/min/1.73 m2
    ).
    The primary factors were physical activity, alcohol consumption, smoking, and
    comorbidities.
    Results: Multivariable analysis revealed that older age, proteinuria, cardiovascular disease,
    diabetes, hyperuricemia, and hypertension were significantly associated with higher odds of
    reduced kidney function. Sufficient physical activity, current alcohol consumption, and being a
    current smoker were significantly associated with lower odds of reduced kidney function.
    However, subgroup analysis by sex revealed that the effects of proteinuria, current alcohol
    consumption, and sufficient physical activity were sex-specific.
    Conclusion: Several risk and beneficial factors for reduced kidney function in adults aged
    65 and above in the United States were identified, but some of them might be sex-specific.
    Further studies are warranted to confirm these findings in other populations and countries
    Relation: International Journal of Public Health,66,p.1-9
    DOI: 10.3389/ijph.2021.1603966
    Appears in Collections:[管理科學學系暨研究所] 期刊論文

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