A SERS method with attomolar sensitivity: a case study with the flavonoid catechin

淡江大學機構典藏 > 理學院 > 化學學系暨研究所 > 期刊論文 > Item 987654321/120072

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題名:	A SERS method with attomolar sensitivity: a case study with the flavonoid catechin
作者:	Huang, Chia-Chi;Chen, Wenlung
關鍵詞:	Raman spectroscopy;Citrate-capped AgNPs;Aggregation agent;Attomolar detection
日期:	2018-01-17
上傳時間:	2021-03-05 12:14:52 (UTC+8)
摘要:	Making good use of interactions between analyte molecules and the metal nanoparticles is key to impact the detection limit in a surface-enhanced Raman scattering (SERS) based detections. SERS was applied to the analysis of catechin and it was found that the relative abundance of catechin in the sample to citrate-capped AgNPs and the aggregation agent NaCl plays a critical role in the quality of detection. At a component volume ratio of 6:2:1 (catechin:AgNPs:NaCl), catechin can be detected at µM levels. When the ratio is 12:2:1, Raman signals are discernible even at the attomolar concentration level (10−18 M). Under these conditions, the SERS mechanisms and the force of laser tweezers function best. The extent of signal enhancement enabled an ultrasensitive and reproducible Raman spectroscopic determination of catechin.
關聯:	Microchimica Acta 185, 120
DOI:	10.1007/s00604-017-2662-9
顯示於類別:	[化學學系暨研究所] 期刊論文

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