Multiple Resonance Fiber-Optic Sensor with Time Division Multiplexing for Multianalyte Detection

機構典藏 > College of Sciences > Graduate Institute & Department of Chemistry > Journal Article > Item 987654321/120064

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Title:	Multiple Resonance Fiber-Optic Sensor with Time Division Multiplexing for Multianalyte Detection
Authors:	Lin, Hsing-Ying;Huang, Chen-Han;Huang, Chia-Chi;Liu, Yu-Chia;Chau, Lai-Kwan
Date:	2012-10
Issue Date:	2021-03-05 12:14:41 (UTC+8)
Abstract:	A proof-of-concept multiwindow fiber-optic sensor utilizing multiple particle plasmon resonance (PPR) of silver nanoparticles and gold nanorods separately on two unclad portions of the fiber for multianalyte detection is demonstrated. The detection is based on intensity interrogation of multiple wavelengths by a single detector. Time division multiplexing is employed to modulate the illumination of dual-wavelength LEDs to induce PPRs for simultaneous real-time and label-free monitoring of two types of biomolecular interactions. Preliminary results reveal that a refractive index resolution of 9 ×10−6 RIU is achieved. Moreover, the measured intensities of two windows independently respond to their respective binding events. The potential of the sensor architecture with multiple sensing windows for cascaded, higher throughput, and multianalyte biochemical detection can be expected.
Relation:	Optics Letters 37(19), p.3969-3971
DOI:	10.1364/OL.37.003969
Appears in Collections:	[Graduate Institute & Department of Chemistry] Journal Article

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