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    題名: Multiple Resonance Fiber-Optic Sensor with Time Division Multiplexing for Multianalyte Detection
    作者: Lin, Hsing-Ying;Huang, Chen-Han;Huang, Chia-Chi;Liu, Yu-Chia;Chau, Lai-Kwan
    日期: 2012-10
    上傳時間: 2021-03-05 12:14:41 (UTC+8)
    摘要: A proof-of-concept multiwindow fiber-optic sensor utilizing multiple particle plasmon resonance (PPR) of silver nanoparticles and gold nanorods separately on two unclad portions of the fiber for multianalyte detection is demonstrated. The detection is based on intensity interrogation of multiple wavelengths by a single detector. Time division multiplexing is employed to modulate the illumination of dual-wavelength LEDs to induce PPRs for simultaneous real-time and label-free monitoring of two types of biomolecular interactions. Preliminary results reveal that a refractive index resolution of 9 ×10−6  RIU is achieved. Moreover, the measured intensities of two windows independently respond to their respective binding events. The potential of the sensor architecture with multiple sensing windows for cascaded, higher throughput, and multianalyte biochemical detection can be expected.
    關聯: Optics Letters 37(19), p.3969-3971
    DOI: 10.1364/OL.37.003969
    顯示於類別:[化學學系暨研究所] 期刊論文


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