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    题名: Association between lifestyle factors and decreased kidney function in older adults: a community-based cross-sectional analysis of the Taipei City elderly health examination database
    作者: Chang, Horng-Jinh;Lin, Kuan-Reng;Lin, Meng-Te;Chang, Junn-Liang
    关键词: Kidney function;Glomerular filtration rate;Exercise;Comorbidity;Risk factor
    日期: 2020-05-08
    上传时间: 2020-12-31 12:10:41 (UTC+8)
    出版者: The Renal Association
    摘要: Background: Impaired kidney function is the hallmark of chronic kidney disease (CKD), and is associated with
    increased risk of all-cause mortality in the elderly. In the present cross-sectional population-based study, we aimed
    to evaluate the associations between lifestyle factors (exercise habit, alcohol consumption, smoking history, and
    betel nut chewing) and decreased kidney function.
    Methods: The data from the Taipei City Elderly Health Examination Database (2006 to 2012) were extracted.
    Associations between risk factors and reduced estimated Glomerular filtration rate (eGFR) were evaluated by
    regression and stratification analyses.
    Results: A total of 297,603 participants were included in the final analysis, and 29.7% of them had reduced eGFR.
    Smoking was significantly associated with an elevated risk of reduced eGFR. While, physical exercise conferred to a
    significantly decreased adjusted odds ratio (aOR) in reduced eGFR (regular exercise, aOR = 0.79; occasional exercise,
    aOR = 0.87). Furthermore, the protective effect of exercise habit against reduced eGFR was not affected by
    comorbid conditions, such as hypertension, diabetes, obesity, and cardiovascular disease.
    Conclusions: Engaging in physical exercise was beneficially associated with reduced eGFR in older individuals.
    Longitudinal or prospective studies are warranted for confirmation and extrapolation of the current findings.
    關聯: BMC Nephrology 21(169)
    DOI: 10.1186/s12882-020-01838-1
    显示于类别:[管理科學學系暨研究所] 期刊論文

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