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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/118076

    Title: Integration of Different Sensory Interventions from Mother’s Breast Milk for Preterm Infant Pain During Peripheral Venipuncture Procedures: A Prospective Randomized Controlled Trial
    Authors: Wu, Hsiang-Ping;Yang, Luke;Lan, Hsiang-Yun;Peng, Hsueh-Fang;Chang, Yue-Cune;Jeng, Mei-Jy;Liaw, Jen-Jiuan
    Keywords: Mother's breast milk;preterm infant pain;sensory intervention;venipuncture
    Date: 2020
    Issue Date: 2020-02-12 12:10:24 (UTC+8)
    Publisher: Wiley
    Abstract: Purpose: To compare the effects of integrating mother’s breast milk (BM)
    with three different combinations of sensory stimuli on preterm infant
    pain during peripheral venipuncture procedures.
    Design: A prospective, repeated-measures randomized controlled trial.
    Methods: Preterm infants (gestational age between 28 and 37 weeks, and
    in stable condition) needing venipuncture were recruited by convenience
    sampling (N = 140) and randomly assigned to four treatment conditions:
    (a) routine care (condition 1); (b) BM odor or taste (condition 2); (c) BM
    odor or taste + heartbeat sounds (HBs; condition 3), and (d) BM odor or
    taste + HBs + non-nutritive sucking (NNS; condition 4). Pain scores were
    assessed based on the Premature Infant Pain Profile-Revised (PIPP-R) over
    nine phases: baseline (phase 0, 5 min without stimuli before venipuncture),
    disinfecting (phase 1), during venipuncture (phase 2), and a 10-min recovery
    (phases 3–8).
    Findings: Infants who received BM odor or taste + HBs + NNS had significantly
    lower increases in pain scores from baseline compared with controls
    across phases 1 through 8. Infants treated with either condition 2 or
    3 demonstrated significant reductions in mild pain during disinfecting and
    recovery phases, as compared with the controls. When condition 2 was
    used as the reference, there were no significant differences in pain scores
    between the infants receiving condition 3 across the nine phases, suggesting
    mothers’ HBs have only mild analgesic effects on venipuncture pain.
    Conclusions: Integration of mother’s BM odor or taste, HBs, and tactile
    NNS should be considered as an intervention for alleviation of procedural
    pain for preterm infants.
    Clinical Relevance: Clinicians should incorporate the integrated sensory
    intervention into caregiving support for preterm infants undergoing short
    painful procedures.
    Relation: Journal of Nursing Scholarship 52 (1), p.75-84
    DOI: 10.1111/jnu.12530
    Appears in Collections:[Graduate Institute & Department of Mathematics] Journal Article

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