新型反應途徑合成類白葉藤鹼

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Title:	新型反應途徑合成類白葉藤鹼
Other Titles:	A novel synthetic route to approach neocryptolepine
Authors:	邱昱綸;Ciou, Yu-Lun
Contributors:	淡江大學化學學系碩士班謝仁傑
Keywords:	夾竹桃科生物鹼;類白葉藤鹼;銅催化;neocryptolepine;Apocynaceae alkaloid;copper-catalyzed
Date:	2016
Issue Date:	2017-08-24 23:38:43 (UTC+8)
Abstract:	第一部分: 以烏爾曼型態的反應方式合成出6H-吲哚[2, 3-b]喹啉及其不同取代基的衍生物。第二部分: 將第一部分的產物往後進行合成，並以總共四步驟的全合成得到類白葉藤鹼，為一種天然生物鹼，在醫藥方面上具相當的應用性。 The 1st Part : We used Ullmann-type reaction to synthesize 6H-indolo[2, 3-b] quinoline and its derivatives. The 2nd Part : We successfully synthesized Apocynaceae alkaloid, Neocryptolepine, in four steps. It has a wide spectrum of application in pharmacology.
Appears in Collections:	[Graduate Institute & Department of Chemistry] Thesis

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