Paenibacillus sp. TKU037所生產α-葡萄糖苷酶抑制劑和抗菌物質之研究

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Title:	Paenibacillus sp. TKU037所生產α-葡萄糖苷酶抑制劑和抗菌物質之研究
Other Titles:	Studies on α-glucosidase inhibitors and antibacterial materials produced by Paenibacillus sp. TKU037
Authors:	施柏豪;Shih, Po-Hao
Contributors:	淡江大學化學學系碩士班王三郎;郭曜豪;Wang, San-Lang;Kuo, Yao-Haur
Keywords:	類芽孢桿菌;α-葡萄糖苷酶抑制劑;抗菌物質;Paenibacillus;α-glucosidase inhibitors;antibacterial materials
Date:	2016
Issue Date:	2017-08-24 23:38:30 (UTC+8)
Abstract:	菌株TKU037係篩選自淡水土壤，液態發酵NB (Nutrient Broth) 能生產α-葡萄糖苷酶抑制劑和抗菌物質，經鑑定係屬類芽胞桿菌（Paenibacillus sp.）之一株細菌。本研究探討Paenibacillus sp. TKU037生產α-葡萄糖苷酶抑制劑之較適條件，以及所生產α-葡萄糖苷酶抑制劑之pH值與熱安定性，並且分離出具α-葡萄糖苷酶抑制活性之一化合物1-methylhydantoin。 Bacterial strain TKU037 produced α-glucosidase inhibitors and antibacterial materials when cultured in nutrient broth (NB). Strain TKU037 was isolated from Taiwanese soils and identified as Paenibacillus species. Optimum culture condition for the production of α-glucosidase inhibitors and the pH and thermal stability of the produced inhibitors have been studied. A compound (1-methylhydantoin) with α-glucosidase inhibitor activity has been isolated from the culture supernatant.
Appears in Collections:	[Graduate Institute & Department of Chemistry] Thesis

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