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    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/110883

    Title: 鈴木耦合反應在合成石蒜科生物鹼之應用
    Other Titles: Application of Suzuki coupling reactions to synthesize Amaryllidaceae alkaloids
    Authors: 范姜岱廷;Chiang, Tai-Ting Fan
    Contributors: 淡江大學化學學系碩士班
    Keywords: 石蒜科生物鹼;DNA拓撲異構酶Ⅰ型;鈴木耦合;Amaryllidaceae alkaloid;DNA topoisomerase Ⅰ;Suzuki coupling
    Date: 2016
    Issue Date: 2017-08-24 23:38:29 (UTC+8)
    Abstract: 第一部分:

    石蒜科生物鹼的全合成,鈴木耦合反應是合成出Galanthindole, Lycosinine A和Lycosinine B的關鍵步驟,另外也發現N-Methylcrinasiadine的另一種合成路徑。
    The 1st Part :
    Synthesize of 2''-bromo-[1, 1''-biphenyl]-2-carbaldehyde derivative with Suzuki coupling reaction and applied to the synthesis phenanthridinium bromide skeleton Amaryllidaceae alkaloids.

    The 2nd Part :
    Strategies for the synthesis of Amaryllidaceae alkaloids. Investigations of optionally synthetic routes to approach N-Methylcrinasiadine were demonstrated as well. In addition, three structurally related alkaloids Galanthindole, Lycosinine A and Lycosinine B were concisely prepared by using Suzuki coupling reaction as the key step.
    Appears in Collections:[化學學系暨研究所] 學位論文

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