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    Please use this identifier to cite or link to this item: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/110592


    Title: Synthesis of phenanthridine skeletal Amaryllidaceae alkaloids
    Authors: Tai-TingFan-Chiang;Hung-KaiWang;Jen-ChiehHsieh
    Keywords: Amaryllidaceae alkaloid;DNA topoisomerase I;Suzuki coupling;Ullmann coupling;SNAr
    Date: 2016-09-08
    Issue Date: 2017-08-01 02:10:15 (UTC+8)
    Abstract: Strategies for the synthesis of Amaryllidaceae alkaloids, including crinasiadine, trisphaeridine, bicolorine, N-methylcrinasiadine, 5,6-dihydrobicolorine, galanthindole, lycosinine A and lycosinine B were reported. Investigation of optionally synthetic routes to approach bicolorine, 5,6-dihydrobicolorine, trisphaeridine and N-methylcrinasiadine were demonstrated as well. In addition, three structurally related alkaloids galanthindole, lycosinine A and lycosinine B were concisely prepared by using Suzuki coupling reaction as the key step.
    Relation: Tetrahedron 72(36), p.5640-5645
    DOI: 10.1016/j.tet.2016.07.065
    Appears in Collections:[化學學系暨研究所] 期刊論文

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