English  |  正體中文  |  简体中文  |  Items with full text/Total items : 49432/84396 (59%)
Visitors : 7457946      Online Users : 65
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/109151

    Title: Effective heating for tumors with thermally significant blood vessels during hyperthermia treatment
    Authors: Huang, Huang-Wen;Liauh, Chihng-Tsung;Horng, Tzyy-Leng;Shih, Tzu-Ching;Chiang, Chi-Feng;Lin, Win-Li
    Keywords: Thermally significant blood vessels;Cooling effect;Hyperthermia;Adaptive optimization;Preheating zone;Absorbed power deposition
    Date: 20130110
    Issue Date: 2017-01-10 02:10:36 (UTC+8)
    Publisher: Pergamon Press
    Abstract: Significant cooling effect by blood vessels, particularly in treated tumor region, during hyperthermia treatment has been recognized by researchers. The present study investigated a heating strategy, using a preheating zone and adaptive optimization, to effectively reduce the cooling effect as thermally significant blood vessels flowed through treated region during hyperthermia treatment. The preheating zone is located in a vessel's entrance region adjacent to treated tumor and the heating strategy attempted to elevate blood temperature before blood flowing into the treated region. We numerically calculated blood and tissue temperatures using 3-D models and the goal of treatment was to reach a uniform therapeutic temperature in the tumor region using the proposed heating strategy. Results showed first, for large blood vessels, the heating strategy effectively elevated blood temperature at the entrance of treated tumor and reduced total tumor power deposition. Consequently, it helped to reach the ideal treated temperature on tumor more effectively, and avoided extreme power deposition due to the cooling effect of blood vessels entering the treated region. For small blood vessels, the preheating zone could further improve the treatment result. Secondly, heating flowing blood with adaptive optimization results in a unique phenomenon along blood flow paths. That is a strong convective nature of blood flow, which creates high thermal gradients in the treated region. Thus, it plays a different and significant role in adaptive optimization process as compared to thermal diffusion of solid tissues.
    Relation: Applied thermal Engineering 50 (1), pp.837-847
    DOI: 10.1016/j.applthermaleng.2012.07.018
    Appears in Collections:[資訊創新與科技學系] 期刊論文

    Files in This Item:

    File Description SizeFormat

    All items in 機構典藏 are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback