English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 60868/93650 (65%)
造訪人次 : 1146897      線上人數 : 17
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜尋範圍 查詢小技巧:
  • 您可在西文檢索詞彙前後加上"雙引號",以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋,建議至進階搜尋限定作者欄位,可獲得較完整資料
  • 進階搜尋
    請使用永久網址來引用或連結此文件: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/107114


    題名: Synthesis and stability study of isocyano aryl boronate esters and their synthetic applications
    作者: Hao-Ping Fang;Chia-Chieh Fu;Chin-Kuen Tai;Ken-Hao Chang;Ru-Han Yang;Meng-Ju Wu;Hsien-Chi Chen;Chia-Jung Li;Shi-Qing Huang;Wan-Hsiang Lien;Chih-Hsin Chen;Chung-Hung Hsieh;Bo-Cheng Wang;Siu-Fung Cheung;Po-Shen Pan
    關鍵詞: boronate ester;isocyanide;multicomponent reaction
    日期: 2016-03-17
    上傳時間: 2016-08-15
    出版者: Royal Society of Chemistry
    摘要: A facile synthesis of isocyano arylboronate esters is reported. Although tri-coordinate boron functional groups are commonly recognized as vulnerable to nucleophilic attack, the newly reported tri-coordinate isocyano arylboronate esters were found to be stable, albeit owing to the presence of an isocyano group. Theoretical calculations, using the DFT/B3LYP/6-31G(d,p) method, revealed that the electron delocalization between the aryl group and the boron atom might contribute to this stability. UV-vis spectroscopic investigations on 2-(4-isocyanophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (2a) were in agreement with the theoretical studies, showing a red-shifted absorption compared with that of phenylisonitrile. The reported strategy allows boronate ester substrates to survive throughout two-step operations. Two of the compounds synthesized were successfully exploited in Ugi and Passerini multicomponent reactions to afford corresponding products. In addition, two boron-containing tetrazoles were also prepared under environmentally benign conditions. These results demonstrated that functionalized isocyanides are stable and can be used as strategically as synthetic building blocks.
    關聯: RSC Advances 6, pp.30362-30371
    DOI: 10.1039/c5ra27624a
    顯示於類別:[化學學系暨研究所] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    index.html0KbHTML225檢視/開啟
    Synthesis and stability study of isocyano aryl boronate esters and their synthetic applications.pdf938KbAdobe PDF3檢視/開啟

    在機構典藏中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回饋