淡江大學機構典藏:Item 987654321/107111
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 62861/95882 (66%)
造访人次 : 4236100      在线人数 : 589
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: https://tkuir.lib.tku.edu.tw/dspace/handle/987654321/107111


    题名: Anti-oxidant and antidiabetic effect of some medicinal plants belong to Terminalia species collected in Dak Lak Province, Vietnam
    作者: Nguyen,Quang-Vinh;Nguyen,Van Bon;Eun, Jong-Bang;Wang, San-Lang;Nguyen, Dinh Hoang;Tran, Thi Nhung;Nguyen, Anh Dzung
    关键词: Antidiabetic activity;α-glucose and α-amylase inhibition;Terminalia species;DPPH radical scavenging
    日期: 2016-06-01
    上传时间: 2016-08-15
    出版者: Springer Netherlands
    摘要: Diabetes mellitus is a chronic disease which is increasing, cannot be cured and so must be suffered for whole life. In recent years, research on herbal medicines for the treatment of diabetes has been increasing. Terminalia species have been used as traditional medicines to treat several diseases including diabetic diseases for a great many years. The aim of this study is to evaluate the anti-oxidant and antidiabetic activities of methanol extracts of the trunk-bark of three Terminalia species, T. alata, T. belirica and T. corticosa Pierre ex Laness. The anti-oxidant activity was determined by DPPH radical scavenging and the antidiabetic activity was determined by digestive enzymes inhibition and lowering fasting blood glucose in diabetic rats. The flavonoids and polyphenol contents were also determined by spectroscopic methods. The results indicated that the three trunk-bark extracts of the investigated plants possessed relatively high anti-oxidant activity with IC50 values of 0.24 mg/ml for T. alata, 1.02 mg/ml for T. belirica and 0.25 mg/ml for T. corticosa and 0.24 mg/ml for the positive control of L-ascorbic acid. In addition, these extracts also exhibited inhibitory activity on α-amylase and α-glucosidase and lowered fasting blood glucose levels in streptozotocin-induced diabetic rats but without inducing body weight loss comparing to acarbose. Amongst the extracts, the highest effect on lowering in diabetic rats was found in the extract of T. belirica followed by T. corticosa and T. alata. However, the extracts did not produce any hypoglycemic effect in normal rats at a dose up to 200 mg/kg body weight. The results suggest that the methanol extracts of the investigated plants may prove to be useful in treating type 2 diabetes.
    關聯: Research on Chemical Intermediates 42(6), p.5859–5871
    DOI: 10.1007/s11164-015-2409-3
    显示于类别:[化學學系暨研究所] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    index.html0KbHTML353检视/开启
    index.html0KbHTML229检视/开启

    在機構典藏中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回馈