English  |  正體中文  |  简体中文  |  Items with full text/Total items : 51296/86402 (59%)
Visitors : 8159758      Online Users : 60
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
  • Adv. Search
    HomeLoginUploadHelpAboutAdminister Goto mobile version
    Please use this identifier to cite or link to this item: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/106392


    Title: Exclusive Genomic Pathway Analysis for Groupers Infected by Different Iridovirus
    Authors: Liu, Chun-Cheng;Chen, Chien-Ming;Pai, Tun-Wen;Chou, Hsin-Yiu;Hsu, Hui-Huang
    Keywords: aquaculture;genomics
    Date: 2015/07/10
    Issue Date: 2016-04-27 11:11:39 (UTC+8)
    Publisher: IEEE
    Abstract: Grouper is one of the most important aquaculture fish in the world. Due to high density of grouper farming, the aquaculture industry is threatened by iridovirus infections in recent years. In this study, we used next-generation sequencing technologies to analyze gene differential expression of groupers infected by two different types of iridoviruses, including Grouper Iridovirus of Taiwan (TGIV) of Megalocytivirus and Grouper Iridovirus (GIV) of Ranavirus. Zebra fish (Danio rerio) was selected as the reference model for gene functional annotations and pathway analyses. According to different fold change levels and identified associated KEGG pathways from defined gene sets, we found exclusive biological characteristics of groupers infected by two different iridoviruses. The results have shown that two specific gene sets, including the first set of PSMB2, CASP3, and U2AF2 for TGIV and the second set of PTGES, PDE3, and THBS1 for GIV were significantly and exclusively expressed. Furthermore, we also found two important pathways, Proteasome and ECM-receptor interaction pathways, were identified by employing gene set/pathway enrichment analysis. These results could facilitate biologists realizing comprehensive gene regulation of groupers infected by different iridoviruses and developing specific vaccines for grouper aquaculture.
    Relation: 2015 Ninth International Conference on Complex, Intelligent, and Software Intensive Systems (CISIS-2015), pp.508-512
    DOI: 10.1109/CISIS.2015.75
    Appears in Collections:[資訊工程學系暨研究所] 會議論文

    Files in This Item:

    File Description SizeFormat
    Exclusive Genomic Pathway Analysis for Groupers Infected by Different Iridovirus_議程.pdf528KbAdobe PDF110View/Open
    index.html0KbHTML52View/Open

    All items in 機構典藏 are protected by copyright, with all rights reserved.


    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - Feedback