English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 58795/92528 (64%)
造访人次 : 645383      在线人数 : 61
RC Version 7.0 © Powered By DSPACE, MIT. Enhanced by NTU Library & TKU Library IR team.
搜寻范围 查询小技巧:
  • 您可在西文检索词汇前后加上"双引号",以获取较精准的检索结果
  • 若欲以作者姓名搜寻,建议至进阶搜寻限定作者字段,可获得较完整数据
  • 进阶搜寻

    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/106341

    题名: Fabrication of asymmetric membranes from polyhydroxybutyrate and biphasic calcium phosphate/chitosan for guided bone regeneration
    作者: Hung-Yin Tai;Earl Fu;Liao-Ping Cheng;Trong-Ming Don
    关键词: Chitosan;Polyhydroxybutyrate;Calcium phosphate;Asymmetric membrane;Guided bone regeneration
    日期: 2014-03-16
    上传时间: 2016-04-22 13:46:43 (UTC+8)
    出版者: Springer Netherlands
    摘要: Chitosan (CS) is known for its biocompatibility,
    antibacterial function, and wound healing acceleration, while calcium phosphate (CP) can promote bone regeneration.However, to be useful as barrier membrane for guided bone regeneration (GBR) in periodontal treatments, the membranes must have suitable mechanical strength in addition to good
    barrier properties. Therefore, a dense polyhydroxybutyrate (PHB) layer was integrated with a porous biphasic calcium phosphate/chitosan (BCP/CS) layer to form an asymmetric PHB-BCP/CS membrane. Moreover, for enhancing the interfacial strength, the PHB layer was chemically bonded to the BCP/CS layer through plasma-induced grafting of poly(acrylic
    acid) on its surface and followed by amidation with CS via carbodiimide activation. The incorporation of the PHB layer greatly increased the initial modulus and ultimate tensile strength of the membrane up to 524 and 16.5 MPa, respectively. In addition, the human gingival fibroblast (HGF) cells could proliferate very well on the PHB layer of the membrane, yet they were prohibited from down-growing through the
    membrane. Also, the addition of BCP particles in the CS layer increased the proliferation of osteoblast cells. Thus, the asymmetric PHB-BCP/CS membrane has the potential to be used as a barrier membrane for GBR in periodontal tissue engineering
    關聯: Journal of polymer research 21, 421(11pages)
    DOI: 10.1007/s10965-014-0421-8
    显示于类别:[化學工程與材料工程學系暨研究所] 期刊論文


    档案 描述 大小格式浏览次数



    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library & TKU Library IR teams. Copyright ©   - 回馈